All home games will be played at HSBC Arena in downtown Buffalo. Games start at 7:05.
| Preseason | Date | Opponent | Venue | Result | Record |
Scrimmage | Sunday, August 23 | Kansas City Tigers | Allstate Arena* | L, 42-52 | - |
Crab Cake Semis | Sunday, August 30 | Baltimore Breakers | First Mariner Arena** | W, 52-46 | - |
Crab Cake Final | Sunday, September 6 | Long Island Mean Machine | First Mariner Arena | W, 45-42 | - |
| Regular Season | Date | Opponent | Venue | Result | Record |
| Week 1 | Sunday, September 13 | New England Sno-Dogs | L, 34-37 | 0-1 | |
| Week 2 | Sunday, September 20 | Long Island Mean Machine | HSBC Arena | L, 51-52 (2OT) | 0-2 |
| Week 3 | Sunday, September 27 | Connecticut Cresleys | HSBC Arena | W, 46-39 | 1-2 |
| Week 4 | Sunday, October 4 | Detroit Gladiators | W, 22-16 | 2-2 | |
| Week 5 | Sunday, October 11 | Philadelphia Colonials | HSBC Arena | W, 41-31 | 3-2 |
| Week 6 | Sunday, October 18 | Fort Dodge Roughriders | L, 39-46 | 3-3 | |
| Week 7 | Sunday, October 25 | Miami Maulers | HSBC Arena | W, 40-24 | 4-3 |
| Week 8 | Sunday, November 1 | Rocky Mountain Reign | HSBC Arena | W, 45-42 | 5-3 |
| Week 9 | Sunday, November 15 | Portland Pioneers | |||
| Week 10 | Sunday, November 22 | Omaha Xplosion | HSBC Arena | ||
| Week 11 | Sunday, November 29 | Evansville Fightin' Squirrels | |||
| Week 12 | Sunday, December 6 | Long Island Mean Machine | |||
| Week 13 | Sunday, December 13 | Connecticut Cresleys | |||
| Week 14 | Sunday, December 20 | Detroit Gladiators | HSBC Arena | ||
| Week 15 | Sunday, December 27 | Philadelphia Colonials | |||
| Week 16 | Sunday, January 3 | New England Sno-Dogs | HSBC Arena |
(Home Games in Orange and Bold)
(Neutral Site Games in Yellow)
* - Allstate Arena is located in Rosemont, Illinois.
**- First Mariner Arena is located in Baltimore, Maryland.